Exploring the Pros and Cons of HRT: A Pharmacist’s Guide

Hot flushes, night sweats, fatigue, low mood — are these symptoms far too real for you?

Unsure whether to try hormone replacement therapy (a.k.a HRT)? 

Well then, you're in the right place...

Welcome to our handy Pharmacist’s Guide. 

Many women think HRT is a complicated subject, but it doesn't have to be.

We believe passionately that women must be well-informed in order to make the best choices for themselves. In this article, we address some of the most common myths about HRT, as well as how it acts in the body and the possible benefits and drawbacks of using it.

Written by Elizabeth Japal, Pharmacist and Co-founder of The Derma Lab, an Aesthetics Treatment Clinic.

We will be covering:

• A breakdown of HRT: What it is, the types, and how it works.
• Benefits of HRT: Relief of menopausal symptoms, bone health, cardiovascular health, and quality of life improvements.
• Risks and drawbacks of HRT: Potential cancer risks, cardiovascular risks, common side effects, and long-term uncertainties.
• Pharmacist’s perspective: How pharmacists assess and personalise HRT, the importance of patient counselling, and collaboration with healthcare providers.
• Possible alternatives to HRT: Lifestyle changes, non-hormonal medications, and natural remedies.

PSA: You can absolutely take Valerie Daily Essential alongside HRT – and they make a brilliant duo.

Just to clear it up: there are no interactions between HRT and any of the ingredients in Valerie Daily Essential. That's a fancy word doctors use that basically means nothing in our formula interferes with or blocks the effects of HRT medication.

What makes HRT and Daily Essential such a great team?

So if you’re using HRT to get your hormones back on side, Valerie’s Daily Essential can step in with extra support:

HRT works on your hormone levels, while Valerie Daily Essential brings the reinforcements, from magnesium and vitamin B6 for mood, to vitamin D3 and K2 for bones, plus iron and B12 for energy. It’s a full-body double act that helps you get back to being yourself again. (More on this later...)

In short, HRT and Daily Essential are different tools, but they’re playing on the same team. So you can tackle your symptoms and get back to feeling like a boss.

Hormone Replacement Therapy (HRT) involves supplementing the body with hormones, primarily oestrogen and progesterone, to alleviate symptoms associated with menopause. It is primarily used to treat hot flushes, night sweats, mood swings, and other menopausal symptoms.

Types of HRT: finding the right fit

There’s no one-size-fits-all when it comes to HRT. Different types are available to suit your symptoms, medical history and where you are in the menopause journey.

• Oestrogen-only HRT: Prescribed for women who have had their uterus (womb) removed during a hysterectomy. Oestrogen-only HRT products are available as tablets, patches, sprays or gels.
• Combined HRT: Contains both oestrogen and progesterone, suitable for women who still have their uterus. Taking both hormones reduces the risk of developing womb cancer. The hormones may be available as separate HRT products or combined within a single product.
• Bioidentical Hormones: Hormones that are chemically identical to those the human body produces. They can be compounded individually for patients but are often debated in terms of safety and efficacy.

Think of HRT as a bit of a top-up, just like someone topping up your wine glass when it’s looking a little empty on a Friday night.

It replaces the oestrogen and progesterone your body has gradually started cutting back on during menopause. This helps balance your hormone levels and reduce common symptoms like hot flushes, brain fog and mood swings.

HRT can be given in cycles or as a steady daily dose. The type you need depends on your symptoms and what stage of menopause you are in.

It’s all about finding what works best for your body.

When hormones start playing havoc, HRT can help bring some much-needed decorum to those who find relief from it.

It turns the volume down on symptoms

One of the primary benefits of HRT is the significant relief from menopausal symptoms. It effectively reduces hot flushes, night sweats, and mood swings, improving overall comfort and quality of life during menopause.

Your bones might thank you

HRT plays a crucial role in maintaining bone density. Oestrogen helps prevent bone density loss, reducing the risk of osteoporosis and fractures, which are more common post-menopause due to the decrease in oestrogen levels.

It could help your heart

Some studies suggest that HRT may have cardiovascular benefits when started near the onset of menopause (1). Oestrogen has a protective effect on your heart and as levels begin to fall prior to and during menopause, fat can build up in your arteries and cholesterol levels can begin to rise.

Oestrogen, which is found in HRT, helps to prevent the build up of fat within blood vessels and also helps to maintain the elasticity of blood vessels, potentially reducing the risk of heart disease by keeping your blood vessels healthy.

It may even make life a bit more liveable again

Many women report an improved quality of life when using HRT. The alleviation of symptoms allows for better sleep, mood, and energy levels, enabling women to maintain their usual activities and overall well-being.

So to wrap up, from hot flushes to bone strength to heart health, the benefits can be wide-reaching, and for many, life feels that bit more manageable (1).

The other side of the story: the risks (1)

Being fully informed means knowing both the benefits and the potential risks. HRT can offer relief for many women, but it isn’t suitable for everyone.

Therefore, understanding the possible drawbacks is essential when deciding if it’s the right option for you.

Cancer risk

One of the most significant concerns with HRT is the potential increased risk of certain cancers:

• Breast cancer: Some studies have indicated an elevated risk of breast cancer with long-term use of combined and oestrogen-only HRT. Combined HRT affects breast cancer risk more than oestrogen-only.  
• Ovarian cancer: There is a small increased risk of ovarian cancer associated with all types of HRT, although the risk diminishes after discontinuation.
• Womb (endometrial) cancer: Oestrogen-only HRT increases the risk of womb cancer. This is why it is usually only offered to women who have had a hysterectomy. 

It is worth noting that the risk of cancer for all types of HRT reduces once the HRT is stopped. 

Cardiovascular risks

The relationship between HRT and cardiovascular health is complex:

• Heart disease: While HRT may benefit heart health if started early, it can increase the risk of heart disease if begun many years after menopause.
• Stroke: HRT has been associated with a slightly increased risk of stroke, particularly in older women.

Common side effects

Common side effects of HRT include:

• Weight gain
• Bloating
• Breast tenderness
• Mood changes

What we’re still learning

There is ongoing research into the long-term effects of HRT, particularly with compounded or bioidentical hormone therapies. While many women use HRT safely, it’s important to stay informed as new evidence emerges.

A pharmacist’s role in HRT

Pharmacists are often the first point of contact for women considering HRT, offering accessible, expert guidance. From assessment to ongoing support, they play a vital part in helping ensure treatment is safe and effective.

Patient Assessment

Pharmacists play a crucial role in assessing whether a patient is a good candidate for HRT. This involves reviewing medical history, current health status, and individual symptoms to tailor the therapy appropriately.

Personalised therapy

HRT is not one-size-fits-all. Pharmacists work to personalise therapy, ensuring the right type and dosage of HRT is used. Regular monitoring and adjustments are essential to address changing needs and minimise risks.

Offering counselling

Pharmacists are key in educating patients about HRT. They provide information on how to take the medication, potential side effects, and what to expect, ensuring patients are well-informed and comfortable with their treatment plan.

Collaboration with other healthcare providers

Pharmacists collaborate closely with doctors and other healthcare providers to ensure comprehensive patient care. This team approach ensures that all aspects of a patient’s health are considered, providing the best outcomes for HRT therapy.

Lifestyle changes

Non-hormonal strategies can also help manage menopausal symptoms:

• Diet: A balanced diet rich in calcium and vitamin D supports bone health. Phytoestrogen-rich foods like soy may help alleviate symptoms.
• Exercise: Regular physical activity helps manage weight, improve mood, and maintain bone density.
• Stress management: Techniques such as yoga, meditation, and deep breathing can reduce stress and improve overall well-being.

Non-hormonal medications

Several non-hormonal medications can help with menopausal symptoms:

• Antidepressants: Certain SSRIs and SNRIs can reduce hot flushes and mood swings.
• Gabapentin: Typically used for nerve pain, gabapentin can also help reduce hot flushes.

So HRT isn’t the only route. From what’s on your plate to how you move your body, simple lifestyle tweaks can make a real difference. And for some, non-hormonal medications offer extra support, especially when HRT isn’t an option (2).

Traditional herbs for hormonal balance in midlife:

Red clover and black cohosh are two of the best-known natural options. Red clover contains phytoestrogens, plant compounds that mimic oestrogen, while black cohosh has long been used for symptoms like hot flushes and mood swings. Results can vary, but some women swear by them.

Valerie Daily Essential:

This is your foundation, think support better than any sports bra. It’s got your back when hormones throw a wobbly, Valerie Daily Essential delivers 12 evidence-based nutrients using advanced liposomal technology — which means your body actually absorbs them, instead of waving them off down the loo.

What’s inside Valerie Daily Essential?

Only the good stuff. Every ingredient’s been picked to help you handle the highs, lows and hormonal chaos of perimenopause. Your energy, mood and focus all get a boost where it counts, with a little help from our friends:

Ashwagandha: Your cortisol calmer. Helps reduce anxiety, ease stress, and bring you back down to earth.

Magnesium: The mood and hormone multitasker. Helps regulate cycles, lift mood and boost bone health.

Vitamin B6: Mood-swing manager and fatigue fighter. Supports serotonin production, so you feel more you.

Vitamin D3: Sunshine in a shot. Supports mood, immunity and energy, especially when grey skies hit.

Vitamin K2: Keeps bones stronger for longer. Helps your body use calcium properly.

Vitamin B12: Brain fog clearer and energy lifter. Good if you’re running off fumes.

Iron: Helps fight tiredness, especially if periods are still doing their thing.

Zinc: Skin, joints and immunity ally. Keeps you glowing and going.

Chromium: Helps manage blood sugar and curb those mid-afternoon snack attacks.

Selenium: Thyroid whisperer. Vital for metabolism, mood and luscious hair.

Vitamin C: Skin, joints and immunity support, plus it helps absorb that iron properly.

Curcuminoids: Anti-inflammatory firepower for memory, attention and achy bits.

It is important to consult with healthcare providers before starting any new supplements to ensure safety and avoid interactions with other medications.

Learn more about our formula.

Hormone Replacement Therapy offers significant benefits in relieving menopausal symptoms, improving bone health, and potentially aiding cardiovascular health. However, it also carries risks, including potential cancer and cardiovascular concerns, as well as common side effects.

Making the right choice for you

Weighing the pros and cons of HRT is essential. It is important to consider individual health needs, preferences, and risks.

Consult with your healthcare providers, including your pharmacist, to make an informed decision about whether HRT is right for you.

And remember, pharmacists can provide valuable insights and personalised guidance to ensure the best possible outcomes.

Pharmacists are experts in medicines and a valuable resource when considering HRT. They can help you understand the options available, both through the NHS and private clinics, and support you in making informed decisions about your care.

Why speak to a pharmacist about HRT?

Pharmacists are often more easily accessible than GPs so always consider having a chat with your local pharmacist first.

Getting support beyond your GP

Pharmacists may be able to prescribe if working within a private HRT clinic or even within your NHS GP practice.

If you have been prescribed HRT by your GP, Pharmacists can also offer advice regarding side effects and how to get the best from your medication. Most GP surgeries will have access to a pharmacist's or drop into your local Pharmacy.

Put on your big girl boots. Our hormones know what is best for us, and our winning formula takes the prize! 

Still wondering how Valerie Daily Essential Liposomal Shot can help kick some proverbials? Well then, take a sneak peek and find out!

Further Reading

For more information on HRT, consider these reputable sources:

• NHS website
• British Menopause Society
• Cancer Research UK
• British Heart Foundation

Disclaimer:

The information provided in this article is for general informational purposes only and does not constitute medical advice. Always consult your doctor, pharmacist, or other qualified healthcare professional before making any decisions regarding hormone replacement therapy (HRT) or other health treatments. The content in this article should not be used as a substitute for professional medical advice, diagnosis, or treatment tailored to your individual health needs.